An Interview with Carl Djerassi

Wolfson :   If you could be reborn, what would you choose to be? Man? Woman? Animal? Microbe?
Djerassi :   Oh, not a microbe, under no condition. I think it would be interesting to be a woman, now. A modern woman would be very interesting because things are changed. It is exciting to be an American woman. I think, in many other countries, it is not the case yet. I certainly would not want to be a Japanese woman, I can tell you that right away. Or an Afghani woman. But here, it would be interesting because I could be breaking into territory that has not been friendly territory.

I would like to live in the 19th century -- only with a word processor. I have always wondered how Dickens managed.

I might well become a scientist, but I would not become a chemist. As a scientist, I think I would become a molecular biologist, geneticist, neuroscientist, something in that borderline area of biology and chemistry.

The other thing would be is to be a musician. I used to play the cello, just an amateur cellist, but I enjoyed it greatly. I didn't have the time to continue it, when I was in my 20s. I am very sorry that I gave that up.


I don't think it should be necessary to be married three times before you have learned all the lessons, even twice ought to be enough.
Wolfson :   How about an historical period that you feel most suited to. When would you have liked to have lived?
Djerassi :   Probably the late 19th century. That would be a very exciting time, yet many of the frenetic aspects were not there yet. The fact that we didn't have airplanes or even cars was not really critical. I would like to live in the 19th century -- only with a word processor. I have always wondered how Dickens managed, or Trollop.
Wolfson :   What has been your biggest screw-up?
Djerassi :   My successful marriage was my third marriage. I don't think it should be necessary to be married three times before you have learned all the lessons, even twice ought to be enough.

The role of parent that I played was a very traditional one, and it is not one that I would probably play now if I were to do it all over again. Of course, I don't even know whether I would want to have children if I were to do it over again.

Wolfson :   What is your most treasured possession?
Djerassi :   You mean, other than other human beings? Probably my collection of Paul Klee. I collect other artists, but Klee is an obsession. But otherwise,

I would say that physical possessions are not of enormous importance to me.

Wolfson :   Describe your version of happiness.
Djerassi :   I don't know how to describe it because I'm not sure that I was ever truly happy. I can probably describe it at best as satisfaction and contentment. But I have tremendous ups and downs along these lines. I don't think that I am an inherently happy person. But I'm certainly not a bitter dark person, either. I fluctuate very much.

I have had a number of real tragedies in my life, by far the biggest one was the suicide of my daughter.

And I have a fused knee from a skiing accident. When it happened to me, it seemed like a terrible tragedy, yet it kept me out of the army. So in that respect you can say that I was lucky. This was why I was able to get through college earlier and I was able to do things that my colleagues could not do, many of whom didn' t survive the war. You might even say that if this guy Hitler's disaster had not happened in Europe, I would not have been a scientist. I would probably have been a practicing physician.

Wolfson :   How do you think your friends, the ones who know you best, would describe you?
Djerassi :   As a very ambitious person. They would say it probably in a positive context rather than a negative one. They might use compliments saying that I managed to accomplish so much in their eyes. in a unit time. But there's the other side of the coin. But I think I have paid a price for that. My door would not be open, people would not just pop in.

We all know we will die sometime, but death is clearly not a preoccupation, in your mind and it wasn't in mine. But then suddenly I did not know if I would survive.

Now, of course, I also know the value of human interaction. I don't think I learned that until 12 years ago when I was about to go on a trek to the Himalayas and I had to have a physical exam for the higher altitude exposure. The diagnosis said that I had cancer, so I ended up in a hospital bed in an operating room, rather than up in the Himalayas. That's when I really came to terms with my mortality.

We all know we will die sometime, but death is clearly not a preoccupation, in your mind and it wasn't in mine. But then suddenly I did not know if I would survive. If I had known this, would I have led a different life? The answer is Yes. In fact, that's when I started writing fiction. So out of the cancer came something positive.

Chien :   You collect all kinds of art, objects, paintings, and so forth...
Djerassi :   Well, at one time, I collected primarily the works of very famous artists. I sold all my art, with the exception of the Klees which I still have, about 10 years ago or so, to form an artists' colony. This supports living, working artists because I really felt I could do nothing for dead artists. You know, I can do nothing for Paul Klee. He is either up in Heaven or down in Hell. But I can do something for contemporary artists, and so I used that money to fund the colony.

I think that art, in general, is the difference between us and animals who eat, reproduce, and exist.

I am also interested in primitive art. I have a good Mexican, pre-Columbian collection. I have always been interested in archaeology, that's another life I might well have led seriously.

Chien :   Do you think art serves any specific purpose in building society?
Djerassi :   Absolutely. I think that art, in general, is the difference between us and animals who eat, reproduce, and exist. And also it reflects the progress and the record of human activity, which is very different from just the simple written word. It can express things that we cannot express in just words.

Chien: So if a simple organic organism could create art or express itself ... if it could not communicate verbally or in any way acceptable to us, but it did create art, then it would be a higher life form?


It can express things that we cannot express in just words.

Djerassi: I don't mean the argument that if you put a chimp in front of a typewriter, and it pounds long enough on a typewriter, it creates Shakespeare. You know that stupid argument! I'm talking about conscious activity. If it is in just completely plain language that describes a very simple story from A to B to C to D to E that gives no leeway with respect to interpretation or anything else, that's not,

Wolfson :   Let's talk about science here. Pure science, birth control, sperm, pregnancy. What are we going to see in the future in the area of reproductive biology?
Djerassi :   On the one hand, over the short term, I am very pessimistic about any fundamentally new method of birth control being developed for the next 20 years, or maybe even 30 years. I'm talking about new methods of birth control. I'm not talking necessarily about people using existing methods more effectively.

With a vaccine, we could vaccinate everyone after puberty, so they become infertile and stay infertile. That is their natural state, unless they do something conscious to become fertile. Now that, I think, would be much more sensible in many respects.

But in the longer term, in the middle of the next century, I think that one of the really new methods of birth control will be immunization and vaccination. And that could fundamentally change what fertility is all about.

In our present state of affairs, during our reproductive years, unless we do something consciously to be infertile, which is to take some birth control device, we are fertile. With a vaccine, we could vaccinate everyone after puberty, so they become infertile and stay infertile. That is their natural state, unless they do something conscious to become fertile. Now that, I think, would be much more sensible in many respects. What it does mean, however, is that we separate the processes of procreation basically from spontaneous sexual intercourse.

You could even separate it completely from sexual intercourse, incidentally. It could be a test tube operation, which is already used now for many infertile people. You don't have any mind-blowing orgasm in which you think you just fertilized a child, which is what people romanticize about. It is total romanticization, because of course, you never know when an egg is fertilized. Things could be separated, so that then, in theory, every child that is born is a wanted child. That to me is a desirable thing.

We could learn so much more about genetics without talking about any form of objectionable eugenics. It would be possible to determine any serious genetic abnormalities that could be prevented. There will be many more sophisticated methods to insure that both the egg is a good one. Thirty to 40 percent of all fertilized eggs get ejected in menstrual flow because something is wrong with them, so you might as well pick a good egg of yours and a good sperm of mine, or the best ones we've got, so to speak. Some people think this idea is terrible, and call it test-tube babies.


It suggested that young man should be willing to be sterilized, have a vasectomy, but first preserve their sperm in a sperm bank. You could use artificial insemination afterwards. That is a very reasonable approach. Men can take the responsibility.

This is all related to the abortion question. Abortion should be unnecessary. Everyone should be willing to agree with that. Now the only way to make it unnecessary is to only have sex when you want to have children, which would be the Papal answer. Or, you practice contraception. But the moment you practice contraception, then you are already separating sexual intercourse as a pleasurable activity, and reproduction as another event. I think this is exactly what we should do. The two things should not necessarily be combined.

And the moment you accept that, then I think doing some things, that are not in my opinion, high tech things, there is nothing mysterious about them, they are not test-tube babies in the Frankenstein sense at all.


The thing that I like least about America is that it is still basically a very violent society. This obsession with guns is something which I know of in no civilized country, even wild ones.

I made a proposal in a scientific journal. It suggested that young man should be willing to be sterilized, have a vasectomy, but first preserve their sperm in a sperm bank. You could use artificial insemination afterwards. That is a very reasonable approach. Men can take the responsibility.

Chien :   Do you have any advice for the young people or children in society right now?
Djerassi :   The thing that I like least about America is that it is still basically a very violent society. This obsession with guns is something which I know of in no civilized country, even wild ones. I would say if this could be a gun-free society, I think that would make an unbelievable impact in this country. I'm a worshipper of intellectual strength, rather than physical strength.